165460-09-3Relevant articles and documents
Asymmetric synthesis of cyclohex-2-enols: The examples of seudenol and analogues
Bueno,Carmen Carreno,Garcia Ruano,Hamdouchi
, p. 1237 - 1240 (1995)
An efficient synthesis of enantiomerically pure cyclohex-2-enols from the reaction of 2-p-tolylsulfinyl cyclohexanols with (CF3CO)2O/Py and subsequent hydrogenolysis of the C-S bond with Li/Naphthalene, is reported. This strategy has been applied to the asymmetric synthesis of seudenol and 1-methylcyclohex-2-en-1-ol. New data on the rearrangement of the trifluoroacetate group when 2-p-tolylsulfinyl 1-methylcyclohexenols are treated under the Pummerer reaction conditions are also reported.