1655-51-2

Basic information

• Product Name: DNP-L-TRYPTOPHAN
• Synonyms: DNP-L-TRYPTOPHAN;N-2,4-DNP-L-TRYPTOPHAN;DNP-L-Tryptophan 2,4-Dinitrophenyl-L-tryptophan;N-(2,4-dinitrophenyl)-L-tryptophan;Nα-(2,4-Dinitrophenyl)tryptophan;L-Tryptophan, N-(2,4-dinitrophenyl)-;Nsc526958;(S)-2-((2,4-Dinitrophenyl)aMino)-3-(1H-indol-3-yl)propanoic acid
• CAS NO: 1655-51-2
• Molecular Formula: C₁₇H₁₄N₄O₆
• Molecular Weight: 370.32
• EINECS: 216-738-3
• Mol File: 1655-51-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 699.6°Cat760mmHg
• Flash Point: 376.9°C
• Appearance: /
• Density: 1.584g/cm³
• Vapor Pressure: 1.53E-20mmHg at 25°C
• Refractive Index: 1.763
• Storage Temp.: −20°C
• CAS DataBase Reference: DNP-L-TRYPTOPHAN(CAS DataBase Reference)
• NIST Chemistry Reference: DNP-L-TRYPTOPHAN(1655-51-2)
• EPA Substance Registry System: DNP-L-TRYPTOPHAN(1655-51-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1655-51-2(Hazardous Substances Data)

Usage

General Description

DNP-L-tryptophan is a chemical compound that is a derivative of the amino acid tryptophan. It is often used in research and pharmaceutical applications as a precursor for the synthesis of tryptophan-containing peptides and proteins. DNP-L-tryptophan has a range of potential biological and pharmaceutical applications, including being used as a building block in the development of novel pharmaceuticals and as a tool for studying the structure and function of proteins. It is also used in the field of biochemistry and molecular biology to investigate the relationship between the structure and function of proteins, and to explore the potential therapeutic applications of tryptophan-containing compounds.

InChI:InChI=1/C17H14N4O6/c22-17(23)15(7-10-9-18-13-4-2-1-3-12(10)13)19-14-6-5-11(20(24)25)8-16(14)21(26)27/h1-6,8-9,15,18-19H,7H2,(H,22,23)

Upstream product

• 63628-23-9 N-(2,4-dinitrophenyl)-D,L-tryptophan 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 73-22-3 L-Tryptophan 

Relevant articles and documents

Direct resolution of optically active isomers on chiral packings containing ergoline skeletons. 5. Enantioseparation of amino acid derivatives

A new procedure for ergot alkaloid-based chiral stationary phase preparation is described. Synthesis is based on bonding the allyl derivative of terguride to mercaptopropylsilanized silica gel. The packing exhibits higher content of chiral selector, stability, reproducibility, and enantioselectivity toward amino acids compared to that previously studied. The chromatographic behavior of amino acids with different side chains and substituent groups is investigated in order to obtain a deeper insight into the enantiodiscriminative mechanism as well as to determine the limitations and strengths of terguride as a chiral selector for this class of compounds. A variety of factors, including mobile phase parameters such as pH, ionic strength, content and nature of organic modifier, and temperature, are examined. A new procedure for ergot alkaloid-based chiral stationary phase preparation is described. Synthesis is based on bonding the allyl derivative of terguride to mercaptopropylsilanized silica gel. The packing exhibits higher content of chiral selector, stability, reproducibility, and enantioselectivity toward amino acids compared to that previously studied. The chromatographic behavior of amino acids with different side chains and substituent groups is investigated in order to obtain a deeper insight into the enantiodiscriminative mechanism as well as to determine the limitations and strengths of terguride as a chiral selector for this class of compounds. A variety of factors, including mobile phase parameters such as pH, ionic strength, content and nature of organic modifier, and temperature, are examined.