165544-83-2Relevant academic research and scientific papers
A New Approach to Functionalized Cyclobutanes: Stereoselective Synthesis of the Enantiomers of Grandisol and Fraganol
Martin, Tomas,Rodriguez, Carmen M.,Martin, Victor S.
, p. 1151 - 1164 (2007/10/02)
Enantiomerically enriched (+)-grandisol and (+)-fraganol were synthesized using as the key step a new stereoselective synthesis of cyclobutanes fused to γ-lactones by a stereochemically-controlled intramolecular alkylation of α-benzenesulfonyl-γ-lactones.This method provides a way to synthesize the enantiomers in a straightforward manner.
