16557-52-1

Basic information

• Product Name: (R)-1,1,2-Triphenylbutane
• Synonyms: (R)-1,1,2-Triphenylbutane
• CAS NO: 16557-52-1
• Molecular Formula: C₂₂H₂₂
• Molecular Weight: 286.41
• Mol File: 16557-52-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-1,1,2-Triphenylbutane(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1,1,2-Triphenylbutane(16557-52-1)
• EPA Substance Registry System: (R)-1,1,2-Triphenylbutane(16557-52-1)

Safety Data

• Hazardous Substances Data: 16557-52-1(Hazardous Substances Data)

Upstream product

• 63019-13-6 but-1-ene-1,1,2-triyltribenzene 
• 16282-16-9 1,2-diphenyl-butan-1-one 

Relevant articles and documents

Asymmetric Hydrogenation of Unfunctionalized Tetrasubstituted Acyclic Olefins

Asymmetric hydrogenation has evolved as one of the most powerful tools to construct stereocenters. However, the asymmetric hydrogenation of unfunctionalized tetrasubstituted acyclic olefins remains the pinnacle of asymmetric synthesis and an unsolved challenge. We report herein the discovery of an iridium catalyst for the first, generally applicable, highly enantio- and diastereoselective hydrogenation of such olefins and the mechanistic insights of the reaction. The power of this chemistry is demonstrated by the successful hydrogenation of a wide variety of electronically and sterically diverse olefins in excellent yield and high enantio- and diastereoselectivity.