1656-83-3

Usage

Uses

Used in Pharmaceutical Industry:
D-1-PALMITIN-2-OLEIN is used as a pharmaceutical agent for its potential therapeutic applications. It has been found to possess anti-inflammatory, anti-apoptotic, and anti-oxidative properties, making it a promising candidate for the treatment of various diseases, including neurodegenerative disorders, cardiovascular diseases, and cancer.
Used in Cosmetic Industry:
D-1-PALMITIN-2-OLEIN is used as an ingredient in cosmetic products for its moisturizing and emollient properties. It helps to maintain the skin's hydration and elasticity, providing a smooth and supple texture. It is commonly used in creams, lotions, and other skincare formulations.
Used in Food Industry:
D-1-PALMITIN-2-OLEIN is used as a food additive for its emulsifying and stabilizing properties. It helps to improve the texture, consistency, and shelf life of various food products, such as baked goods, confectionery, and dairy products.
Used in Research:
D-1-PALMITIN-2-OLEIN is used as a research tool in the study of lipid metabolism, cell signaling, and membrane biology. It aids in understanding the role of lipids in various cellular processes and their implications in health and disease.

Upstream product

• 57-10-3 1-hexadecylcarboxylic acid 
• 30563-15-6 1-O-trityl-3-O-palmitoyl-sn-glycerol 
• 143003-65-0 (2R)-3-(benzyloxy)-2-hydroxypropyl hexadecanoate 

Relevant academic research and scientific papers

Is the Mirror Image a True Reflection? Intrinsic Membrane Chirality Modulates Peptide Binding

Peptides with pharmaceutical activities are attractive drug leads, and knowledge of their mode-of-action is essential for translation into the clinic. Comparison of native and enantiomeric peptides has long been used as a powerful approach to discriminate membrane-or receptor-mediated modes-of-action on the basis of the assumption that interactions with cell membranes are independent of peptide chirality. Here, we revisit this paradigm with the cyclotide kalata B1, a drug scaffold with intrinsic membrane-binding activity whose enantiomer is less potent than native peptide. To investigate this chirality dependence, we compared peptide-lipid binding using mirror image model membranes. We synthesized phospholipids with non-natural chirality and demonstrate that native kalata B1 binds with higher affinity to phospholipids with chirality found in eukaryotic membranes. This study shows for the first time that the chiral environment of lipid bilayers can modulate the function of membrane-active peptides and challenges the view that peptide-lipid interactions are achiral.

Synthetic phospholipids as specific substrates for plasma endothelial lipase

We designed and prepared synthetic phospholipids that generate lyso-phosphatidylcholine products with a unique mass for convenient detection by LC–MS in complex biological matrices. We demonstrated that compound 4, formulated either as a Triton X-100 emulsion or incorporated in synthetic HDL particles can serve as a substrate for plasma EL with useful specificity.

Differential interaction of an AmB Analogue and ergosterol in enantiomeric membranes

An amphotericin B derivative exhibits differential interaction with vesicles formed from either natural (R)-or unnatural (S)-POPC and ergosterol. This implicates a close association between the polyene macrolide and the phospholipid bilayer and may account for its increased antifungal activity.

The efficient synthesis of mixed diacyl phospholipids with polyunsaturated fatty acid in sn-2 position of glycerol

A convenient method for synthesis of the mixed-diacyl phospholipid using boron trichloride as an efficient reagent for the removal of benzyl protecting group from polyunsaturated diacylglycerols without affecting the double bond and acyl migration is desc