16563-41-0

Basic information

• Product Name: 3-(naphthalen-1-yloxy)propanoic acid
• Synonyms: 3-(1-naphthyloxy)propanoic acid
• CAS NO: 16563-41-0
• Molecular Formula: C₁₃H₁₂O₃
• Molecular Weight: 216.2326
• Mol File: 16563-41-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 379.8°C at 760 mmHg
• Flash Point: 147.6°C
• Density: 1.234g/cm³
• Vapor Pressure: 1.91E-06mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 3-(naphthalen-1-yloxy)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(naphthalen-1-yloxy)propanoic acid(16563-41-0)
• EPA Substance Registry System: 3-(naphthalen-1-yloxy)propanoic acid(16563-41-0)

Safety Data

• Hazardous Substances Data: 16563-41-0(Hazardous Substances Data)

Upstream product

• 107-94-8 chloropropionic acid 
• 90-15-3 α-naphthol 
• 58889-08-0 α-naphthyl 2-cyanoethyl ether 

Downstream Products

• 97625-31-5 15-Phenyl-12,15-dihydro-11-oxa-15,16-diaza-cyclopenta[a]phenanthrene-17-carboxylic acid ethyl ester 
• 97625-30-4 15-Phenyl-12,15-dihydro-11-oxa-15,16-diaza-cyclopenta[a]phenanthrene 
• 93416-98-9 3-Bromo-4-oxo-2,3-dihydro-4H-naphtho<1,2-b>pyran 

Relevant articles and documents

Acid activated montmorillonite K-10 mediated intramolecular acylation: Simple and convenient synthesis of 4-chromanones

3-Aryloxyproionic acids undergo intramolecular cyclization in the presence of AA.Mont.K-10 in toluene under reflux for 30–45 min in good to excellent yields. Phenyl ring bearing various substituents at the ortho, meta, para positions undergo this cyclization reaction. This method involves simple work up and amenable for large scale preparations. The heterogeneous acid treated catalyst can be regenerated and used for up to three cycles with minimum loss of activity.

Synthesis of Naphthopyranoisoxazoles and Naphthopyranopyrazoles via Cyanoethylation

-