1658-75-9Relevant academic research and scientific papers
An efficient ZrCl4 catalyzed one-pot solvent free protocol for the synthesis of 4-substituted coumarins
Sharma,Janardhan Reddy,Sree Lakshmi,Radha Krishna
, p. 6119 - 6121 (2005)
A versatile and efficient route to 4-substituted coumarins via a Pechmann reaction using ZrCl4 as the catalyst (10 mol %) is described. This method provides several advantages over alternative procedures such as mild, solvent-free conditions at ambient temperature, and direct isolation of the products in high yields.
