165806-95-1

Basic information

• Product Name: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE
• Synonyms: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE;A-TOSYL-(4-FLUOROBENZYL) ISOCYANIDE;ALPHA-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE;ALPHA-(P-TOLUENESULFONYL)-4-FLUOROBEZYLISONITRILE;[1-(4-FLUOROPHENYL)-1-TOSYL]METHYL ISOCYANIDE;Alpha-tosyl-(4-fluorobenzal)isocyanide;alpha-[(4-Methylphenyl)sulphonyl]-4-fluoroBenzylisonitrile;α-(p-Toluenesulfonyl)-4-fluorobenzylisonitrile
• CAS NO: 165806-95-1
• Molecular Formula: C₁₅H₁₂FNO₂S
• Molecular Weight: 289.32
• Mol File: 165806-95-1.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE(165806-95-1)
• EPA Substance Registry System: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE(165806-95-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 165806-95-1(Hazardous Substances Data)

Usage

Uses

Alpha-(p-toluenesulfonyl)-4-fluorobenzylisonitrile is a useful reagent for the development of DNA-compatible method for novel functionalized imidazoles.

InChI:InChI=1/C15H12FNO2S/c1-11-3-9-14(10-4-11)20(18,19)15(17-2)12-5-7-13(16)8-6-12/h3-10,15H,1H3

Upstream product

• 824-79-3 sodium 4-methylbenzenesulfinate 
• 536-57-2 p-toluene sulfinic acid 
• 459-57-4 4-fluorobenzaldehyde 
• 185243-80-5 N-[(4-Fluoro-phenyl)-formylamino-methyl]-formamide 
• 165806-94-0 N-[(4-fluorophenyl)[(4-methylphenyl)sulfonyl]methyl]formamide 

Downstream Products

• 165806-48-4 5-(2-Aminopyrimidin-4-yl)-4-(4-fluorophenyl)-1-[3-(4-Morpholinyl)propyl]imidazole 
• 165806-68-8 4-(4-Fluorophenyl)-5-[2-(methylthio)-4-pyrimidinyl]-1-[3-(4-morpholinyl)-propyl]imidazole 
• 148890-53-3 4-fluorobenzyl isocyanide 
• 180869-52-7 tert-butyl 4-(4-(4-fluorophenyl)-5-(2-(methylthio)-pyrimidin-4-yl)-1H-imidazol-1-yl)piperidine-1-carboxylate 
• 228551-26-6 1-[(1-t-butoxycarbonyl)piperidin-4-yl]-4-(4-fluorophenyl)-5-[2-(2-propylthio)pyrimidin-4-yl]imidazole 
• 193746-75-7 4-(4-fluorophenyl)-5-(2-methoxypyrimidine-4-yl)-1-(piperidine-4-yl)imidazole 
• 639491-74-0 carbonic acid tert-butyl ester 1-(3-{3-[3-{[1-butylcarbamoyl-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-methyl}-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-propoxy}-phenyl)-allyl ester 
• 692739-56-3 carbonic acid tert-butyl ester 1-(3-{3-[3-[({[1-butylcarbamoyl-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-propoxy}-phenyl)-allyl ester 

Relevant articles and documents

The base-free van Leusen reaction of cyclic imines on water: Synthesis of N-fused imidazo 6,11-dihydro β-carboline derivatives

Construction of imidazoles has been demonstrated on water under base-free conditions. The reaction of dihydro β-carboline imines and p-toluenesulfonylmethyl isocyanides furnished the corresponding substituted N-fused imidazo 6,11-dihydro β-carboline derivatives in very good yields under ambient conditions. The use of deuterium oxide (D2O) as a solvent enabled the incorporation of deuterium isotopes in the imidazole ring.

1,3-DIARYL-SUBSTITUTED HETEROCYCLIC PESTICIDES

Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein Q is and Z1, Z2, J1, J2, M, R1a, R1b, R2a, R2b, R2c, R2d, R14/su

BENZIMIDAZOLES AND BENZOTHIAZOLES AS INHIBITORS OF MAP KIANSE

-