16601-30-2

Basic information

• Product Name: 1-Benzylmercapto-1-acetyl-aceton
• CAS NO: 16601-30-2
• Molecular Weight: 222.308
• Mol File: 16601-30-2.mol

Chemical Properties

• CAS DataBase Reference: 1-Benzylmercapto-1-acetyl-aceton(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzylmercapto-1-acetyl-aceton(16601-30-2)
• EPA Substance Registry System: 1-Benzylmercapto-1-acetyl-aceton(16601-30-2)

Safety Data

• Hazardous Substances Data: 16601-30-2(Hazardous Substances Data)

Upstream product

• 100-53-8 phenylmethanethiol 
• 123-54-6 acetylacetone 
• 100-44-7 benzyl chloride 
• 16601-01-7 benzenethiosulfonic acid S-benzyl ester 

Downstream Products

• 16601-35-7 3,3-Dibenzylmercapto-pentan-2,4-dion 

Relevant articles and documents

Chemoenzymatic Dynamic Kinetic Asymmetric Transformations of β-Hydroxyketones

Herein we report on the development and application of chemoenzymatic Dynamic Kinetic Asymmetric Transformation (DYKAT) of α-substituted β-hydroxyketones (β-HKs), using Candida antartica lipase B (CALB) as transesterification catalyst and a ruthenium complex as epimerization catalyst. An operationally simple protocol allows for an efficient preparation of highly enantiomerically enriched α-substituted β-oxoacetates. The products were obtained in yields up to 95 % with good diastereomeric ratios.