Welcome to LookChem.com Sign In|Join Free

CAS

  • or

166039-62-9

4-(benzylamino)-2-chloro-6-<(triisopropylsilyl)ethynyl>quinazoline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

166039-62-9 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 166039-62-9 Structure

  • Basic information

    1. Product Name: 4-(benzylamino)-2-chloro-6-<(triisopropylsilyl)ethynyl>quinazoline
    2. Synonyms: 4-(benzylamino)-2-chloro-6-<(triisopropylsilyl)ethynyl>quinazoline
    3. CAS NO:166039-62-9
    4. Molecular Formula:
    5. Molecular Weight: 450.099
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 166039-62-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(benzylamino)-2-chloro-6-<(triisopropylsilyl)ethynyl>quinazoline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(benzylamino)-2-chloro-6-<(triisopropylsilyl)ethynyl>quinazoline(166039-62-9)
    11. EPA Substance Registry System: 4-(benzylamino)-2-chloro-6-<(triisopropylsilyl)ethynyl>quinazoline(166039-62-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 166039-62-9(Hazardous Substances Data)

166039-62-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 166039-62-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,0,3 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 166039-62:
(8*1)+(7*6)+(6*6)+(5*0)+(4*3)+(3*9)+(2*6)+(1*2)=139
139 % 10 = 9
So 166039-62-9 is a valid CAS Registry Number.

166039-62-9Relevant articles and documents

Discovery of potent cyclic GMP phosphodiesterase inhibitors. 2-Pyridyl- and 2-imidazolylquinazolines possessing cyclic GMP phosphodiesterase and thromboxane synthesis inhibitory activities

Lee,Konishi,Yu,Miskowski,Riviello,Macina,Frierson,Kondo,Sugitani,Sircar,Blazejewski

, p. 3547 - 3557 (2007/10/03)

Moderate cyclic GMP phosphodiesterase (cGMP-PDE, PDE V) inhibitor 2- phenyl-4-anilino-quinazoline (1) was identified utilizing MultiCASE assisted drug design (MCADD) technology. Modification of compound 1 was conducted at the 2-, 4-, and 6-positions of the quinazoline ring for enhancement of cGMP- PDE inhibitory activity. The 6-substituted 2-(imidazol-1-yl)-quinazolines are 1000 times more potent in in vitro PDE V enzyme assay than the well-known inhibitor zaprinast. The 6-substituted derivatives of 2-(3- pyridyl)quinazoline 84 and 2-(imidazol-1-yl)quinazoline 86 exhibited more than 1000-fold selectivity for PDE V over the other four PDE isozymes. In addition, cGMP-PDE inhibitors 64, 65, and 73 were found to have an additional property of thromboxane synthesis inhibitory activity.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 166039-62-9