16612-53-6Relevant academic research and scientific papers
Complexes of 1,3-bis(2-thiazolylimino)isoindoline with middle and late first row transition metals
Martic, Goran,Engle, James T.,Ziegler, Christopher J.
, p. 1749 - 1752 (2011)
In this communication, we present a study that probes the middle and late first row transition metal chemistry of 1,3-bis(2-thiazolylimino)isoindoline, adding to the known Fe and Cu compounds. Complexes of this ligand with Mn, Co, Zn and a new Fe form are presented and all are structurally characterized by single crystal X-ray methods. The 1,3-bis(2-thiazolylimino)isoindoline ligand can potentially bind via the thiazolyl nitrogen or sulfur atoms; in all of the complexes presented in this report, the N,N,N binding mode is observed exclusively. The ligands bind in a planar configuration, similar to that seen for bis(2-iminopyridyl)isoindoline.
Correlation between the SOD-like activity of hexacoordinate iron(II) complexes and their Fe3+/Fe2+ redox potentials
Kripli, Balázs,Baráth, Gábor,Balogh-Hergovich,Giorgi, Michel,Simaan, A. Jalila,Párkányi, László,Pap, József S.,Kaizer, József,Speier, Gábor
, p. 205 - 209 (2011)
Hexacoordinate, high-spin iron(II) complexes with different isoindoline-derivative ligands have been prepared and characterized. The Fe 3+/Fe2+ redox transition is reversible in each case, but the E1/2 values vary in a ~ 400 mV range depending on the ligand. SOD-like activity of the complexes was determined by indirect methods with cytochrome c, and nitroblue tetrazolium indicator at pH 7.6. The measured activities correlate with the redox potentials for the Fe3+/Fe 2+ couples. The results indicate that the superoxide dismutation takes place via an inner-sphere mechanism at the iron site.
