16618-56-7

Upstream product

• 1635-84-3 2,4-Dimethyl-6-nitroanilin 
• 95-66-9 2,4-dimethylchlorobenzene 

Downstream Products

• 859185-36-7 2-(2,4-dimethyl-6-nitro-anilino)-ethanol 
• 35490-93-8 3,5-Dimethyl-2-(methylthio)-nitrobenzol 
• 35562-51-7 2-chloro-3,5-dimethyl-aniline 
• 1222-09-9 2,4,4'-Trimethyl-6-nitro-diphenylsulfid 
• 35490-71-2 3,5-Dimethyl-2-(methylthio)anilin 
• 58579-99-0 2,4-dimethyl-6-nitro-benzonitrile 
• 860683-36-9 4,6-dimethyl-2-nitrobenzamide 
• 875241-52-4 2-amino-4,6-dimethyl benzamide 
• 1044871-11-5 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethylquinazolin-4(3H)-one 
• 108-69-0 3,5-dimethylaminoaniline 

Relevant academic research and scientific papers

A 3,5-dimethyl aniline method for the preparation of

The invention discloses a preparation method of 3, 5-dimethylaniline. The preparation method is used for preparing the target product 3, 5-dimethylaniline through a reaction of chlorination, nitration and catalytic reductive dechlorination of a ring by taking m-xylene as a raw material. Compared with existing processes, the method disclosed by the invention is few in reaction step and simple in technological process. The yield of 3, 5-dimethylaniline based on m-xylene can reach over 75% of a theoretical amount. The cost of the 3, 5-dimethylaniline can be greatly lowered.

TREATMENT OF DISEASES BY EPIGENETIC REGULATION

The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of cancer, including NUT midline carcinoma, Burkitt's Lymphoma, Acute Myelogenous Leukemia, and Multiple Myeloma; autoimmune or inflammatory diseases or conditions, and sepsis.

COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES

The present disclosure relates to compounds, which are useful for regulating the expression of apolipoprotein A-I (ApoA-I), and their use for treatment and prevention of cardiovascular disease and related disease states, including cholesterol- or lipid-related disorders, such as, for example, atherosclerosis.