166193-95-9

Upstream product

• 166194-08-7 methyl 3-<(tert-butyldiphenylsilyl)oxy>propionate 
• 756-79-6 dimethyl methane phosphonate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 166194-11-2 N-(9-{(3aR,4R,6R,6aR)-6-[(Z)-5-(tert-Butyl-diphenyl-silanyloxy)-3-oxo-pent-1-enyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-benzamide 
• 228262-85-9 {(1S,2R)-1-[(E)-6-(tert-Butyl-diphenyl-silanyloxy)-4-oxo-hex-2-enyl]-2-[(S)-2-(4-methoxy-phenoxy)-1-methyl-ethyl]-cyclopentyl}-carbamic acid benzyl ester 
• 166194-09-8 N⁶-benzoyl-2',3'-isopropylidene-5'-<2-butyl>-N-(tolylsulfonyl)amino>-4-<(tert-butyldiphenylsilyl)oxy>butyl>-5'-deoxyadenosine 
• 166193-99-3 N⁶-benzoyl-2',3'-isopropylidene-5'-<2-<<4-<(tert-butyldiphenylsilyl)oxy>butyl>amino>-4-<(tert-butyldiphenylsilyl)oxy>butyl>-5'-deoxyadenosine 
• 166193-96-0 N⁶-benzoyl-2',3'-isopropylidene-5'-<2-oxo-4-<(tert-butyldiphenylsilyl)oxy>butyl>-5'-deoxyadenosine 

Relevant academic research and scientific papers

Synthesis of pinnaic acid; asymmetric construction of spirocyclic core

An asymmetric synthesis of the spirocyclic core of pinnaic acid, a cPLA2 inhibitor, is described. A key transformation in the sequence involves an asymmetric Michael-initiated ring closure.

Synthesis and Biochemical Evaluation of Adenosylspermidine, a Nucleoside-Polyamine Adduct Inhibitor of Spermidine Synthase

The synthesis of a new class of multisubstrate adduct inhibitors of polyamine biosynthesis has been investigated.The first target compound, designed to inhibit spermidine synthase, was obtained and proved to be a very potent inhibitor of that enzyme.Two s