16625-53-9

Upstream product

• 50-55-5 reserpine 
• 482-85-9 Isoreserpin 
• 68104-24-5 6-methoxy-tryptophyl bromide 
• 70617-03-7 (4aR^*,5S^*,6S^*,7S^*,8aR^*)-6-methoxy-5-(methoxycarbonyl)-7-((3,4,5-trimethoxybenzoyl)oxy)perhydroisoquinoline 
• 75275-97-7 (4aS,5R,6R,8aS)-5-Hydroxymethyl-6-methoxy-7-oxo-octahydro-isoquinoline-2-carboxylic acid methyl ester 
• 96648-96-3 (4aR^*,5S^*,6S^*,7S^*,8aR^*)-2-benzyl-6-methoxy-5-(methoxycarbonyl)-7-((3,4,5-trimethoxybenzoyl)oxy)perhydroisoquinoline 
• 96648-93-0 (4aR^*,5S^*,6S^*,7S^*)-2-benzyl-7-((2'-ethylhexanoyl)oxy)-3,4,4a,5,6,7-hexahydro-6-methoxy-5-((methoxymethoxy)methyl)-1(2H)-isoquinolone 
• 96648-94-1 (4aR^*,5S^*,6S^*,7S^*,8aS^*)-2-benzyl-7-((2'-ethylhexanoyl)oxy)-6-methoxy-5-((methoxymethoxy)methyl)-3,4,4a,5,6,7,8,8a-octahydro-1(2H)-isoquinolone 
• 109961-01-5 (4aR^*,5S^*,6S^*,7S^*,8aS^*)-2-benzyl-5-carboxyl-7-((2'-ethylhexanoyl)oxy)-6-methoxy-3,4,4a,5,6,7,8,8a-octahydro-1(2H)-isoquinolone 
• 96648-95-2 (4aR^*,5S^*,6S^*,7S^*,8aS^*)-2-benzyl-7-((2'-ethylhexanoyl)oxy)-6-methoxy-5-(methoxycarbonyl)-3,4,4a,5,6,7,8,8a-octahydro-1(2H)-isoquinolone 
• 109961-17-3 (4aR^*,5S^*,6S^*,7S^*,8aS^*)-2-benzyl-7-((2'-ethylhexanoyl)oxy)-6-methoxy-5-(methoxycarbonyl)perhydroisoquinoline 
• 109961-00-4 (4aR^*,5S^*,6S^*,7S^*,8aS^*)-2-benzyl-7-((2'-ethylhexanoyl)oxy)-5-hydroxymethyl-6-methoxy-3,4,4a,5,6,7,8,8a-octahydro-1(2H)-isoquinolone 
• 96648-90-7 (4aR^*,5S^*)-2-benzyl-5-((methoxymethoxy)methyl)-3,4,4a,5-tetrahydro-1(2H)-isoquinolone 
• 109961-18-4 (4aR^*,5S^*,6S^*,7S^*,8aR^*)-2-benzyl-7-hydroxy-6-methoxy-5-(methoxycarbonyl)perhydroisoquinoline 

Downstream Products

• 50-55-5 (+/-)-3-isoreserpine 
• 50-55-5 (+/-)-reserpine 
• 109961-20-8 (+/-)-inside 3-isoreserpine 
• 109961-20-8 (+/-)-inside reserpine 
• 75276-05-0 C₄₂H₅₀N₂O₁₂ 
• 75276-07-2 (1S,2R,3R,4aS,13bS,14aS)-8a-Hydroxy-2,11-dimethoxy-3-(3,4,5-trimethoxy-benzoyloxy)-1,2,3,4,4a,5,7,8,8a,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester 
• 75276-08-3 3,4,5-Trimethoxy-benzoic acid (1S,2R,3R,4aS,13bS,14aS)-1-formyl-8a-hydroxy-2,11-dimethoxy-1,2,3,4,4a,5,7,8,8a,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinolin-3-yl ester 
• 75276-06-1 3,4,5-Trimethoxy-benzoic acid (1S,2R,3R,4aS,13bS,14aS)-1-formyl-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinolin-3-yl ester 
• 6242-28-0 3,4,5-Trimethoxy-benzoic acid (1R,2R,3R,4aS,13bS,14aS)-1-hydroxymethyl-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinolin-3-yl ester 
• 482-85-9 Isoreserpin 
• 112547-24-7 (4aS,5S,6R,7R,8aS)-6-Methoxy-7-(3,4,5-trimethoxy-benzoyloxy)-octahydro-isoquinoline-2,5-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

Genaral Strategies for the Synthesis of Indole Alkaloids. Total Syntheses of (+/-)-Reserpine and (+/-)-α-Yohimbine

The concise, total syntheses of the indole alkaloids (+/-)-reserpine (1) and (+/-)-α-yohimbine (4) have been completed by the application of a general strategy that features an intramolecular Diels-Alder reaction for the facile construction of the functio

GENERAL METHODOLOGY FOR CIS-HYDROISOQUINOLINE SYNTHESIS. 3. A SIXTEEN STEP SYNTHESIS OF RESERPINE

A concise synthesis of reserpine is described based on a Diels-Alder cycloaddition, Cope rearrangement sequence for hydroisoquinoline synthesis and on a new procedure for regulating stereochemistry at C-18.