1662702-90-0Relevant academic research and scientific papers
NOVEL COMPOUNDS FOR TREATING DIABETES
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Page/Page column 30, (2018/05/24)
The present invention provides a class of novel aryl pseudo-C-glycoside compounds that are effective for treating diabetes. Also provided are methods for making such compounds and methods for treating diabetes by administering such compounds to patients w
NOVEL PIPECOLIC ACID CO-CRYSTALS OF DAPAGLIFLOZIN AND PROCESS FOR THE PREPARATION THEREOF
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Page/Page column 24, (2017/04/23)
The present invention discloses the process for preparation of (2S,3R,4R,5S,6R)- 2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran- 3,4,5-trioland its amorphous form. The invention further discloses novelco- crystals of dapagliflozin,and process for preparation thereof. The invention further discloses novel intermediateAcetic acid 4,5-diacetoxy-6-acetoxymethyl-2-R1-2- [4-chloro-3-(4-ethoxy-benzyl)-phenyl]-tetrahydro-pyran-3-yl ester, wherein R1 is allyl or 2-prop-2ynyl useful for preparation 2-R1-2-[4-Chloro-3-(4-ethoxy- benzyl)-phenyl]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol.
A NOVEL PROCESS FOR PREPARING (2S,3R,4R,5S,6R)-2-[4-CHLORO-3-(4-ETHOXYBENZYL)PHENY 1] -6-(HY DROXY METHYL)TETRAHYDRO-2H-PY RAN-3,4,5-TRIOL AND ITS AMORPHOUS FORM
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Page/Page column 19, (2016/10/04)
The present invention discloses the process for preparation of (2S,3R,4R,5S,6R)-2-[4- chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol and its amorphous form.
Threefold and chemoselective couplings of triarylbismuths with benzylic chlorides and iodides using palladium catalysis
Rao, Maddali L. N.,Dhanorkar, Ritesh J.
, p. 13134 - 13144 (2014/04/03)
This paper describes the palladium-catalyzed studies on threefold coupling of triarylbismuth reagents with benzylic chlorides and iodides. The optimized protocol conditions are operationally simple, delivering threefold coupling of a variety of triarylbismuths in combination with benzylic chlorides and iodides. The two optimized protocols allowed the synthesis of a diverse range of unsymmetrical diarylmethanes in an efficient manner. As part of this study, chemoselective transformation of benzylic chlorides and iodides was also achieved. This journal is the Partner Organisations 2014.
Pd-catalyzed chemoselective threefold cross-coupling of triarylbismuths with benzylic bromides
Rao, Maddali L. N.,Dhanorkar, Ritesh J.
, p. 6794 - 6798 (2013/05/23)
An efficient palladium-catalyzed protocol was demonstrated for the chemoselective cross-coupling of functionalized benzylic bromides with triarylbismuth reagents. Under the established conditions, catalyzed by palladium in the presence of K3PO
