166271-50-7Relevant academic research and scientific papers
SYNTHESIS OF TETRAHYDRO-1,3-OXAZIN-2-ONES AND -2-THIONES FROM ESTERS OF N-(3-OXOALKYL)CARBAMIC AND -DITHIOCARBAMIC ACIDS
Fisyuk, A. S.,Ryzhova, E. V.,Unkovskii, B. V.
, p. 238 - 242 (1994)
A study has been made of the interaction of N-(3-oxoalkyl)carbamates and -dithiocarbamates with sodium borohydride; it has been shown that, depending on the pH of the reaction medium, the interaction may produce either tetrahydro-1,3-oxazin-2-ones and -2-
Interaction of methyl N-(3-oxoalkyl)carbamates, S-methyl-carbamates, and -dithiocarbamates with sodium borohydride. Synthesis of tetrahydro-1,3-oxazin-2-ones and -thiones
Fisyuk,Ryzhova,Unkovskii
, p. 597 - 609 (2001)
The interaction of N-(3-oxoalkyl)carbamates, -thiocarbamates, and -dithiocarbamates with sodium borohydride has been studied. It was shown that reaction proceeds diastereoselectively, and reductive cyclization with the formation of tetrahydro-1,3-oxazin-2-ones and -thiones may occur. The tend to cyclization of the N-(3-hydroxyalkyl)carbamates, -thiocarbamates, and -dithiocarbamates formed as intermediates depends on the number of substituents in the alkyl chain.
