166317-78-8

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 7786-67-6 isopulegol 
• 13834-07-6 (1R,3R,4S,8R)-9-hydroxy-p-menthol 

Downstream Products

• 166317-80-2 (1R,2S,4S,8R)-2-(3'-oxobutyl)-9-<(triisopropylsilyl)oxy>-p-menthone 
• 166317-79-9 (2S,5R)-5-methyl-2-((R)-1-methyl-2-triisopropylsilanyloxy-ethyl)-cyclohexan-1-one 

Relevant academic research and scientific papers

Structure-activity relationships of the antimalarial agent artemisinin. 3. Total synthesis of (+)-13-carbaartemisinin and related tetra- and tricyclic structures

Provided by total synthesis, endoperoxides 18, 20, and 22 underwent intramolecular oxymercuration-demercuration leading respectively to formation of an isomeric tetracycle, (1aS,3S, 5aS,6R,8aS,9R,125)-10-deoxo-13- carbaartemisinin (19), (+)-10-deoxo-13-ca

Replacement of the nonperoxidic trioxane oxygen atom of artemisinin by carbon: Total synthesis of (+)-13-carbaartemisinin and related structures

Provided by total synthesis, endoperoxides 17, 19 and 21 underwent intramolecular oxymercuration-demercuration leading respectively to formation of an isomeric tetracycle, (1aS,3S,5aS,6R,8aS,9R,12S)-10-deoxo-13-carbaartemisinin 18, (+)-10-deoxo-13-carbaar