166337-57-1

Basic information

• Product Name: 5-methylpyridine-3-sulfonyl chloride
• Synonyms: 5-methylpyridine-3-sulfonyl chloride;5-Methyl-3-pyridinesulfonyl chloride
• CAS NO: 166337-57-1
• Molecular Formula: C6H6ClNO2S
• Molecular Weight: 191.63534
• Mol File: 166337-57-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-methylpyridine-3-sulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methylpyridine-3-sulfonyl chloride(166337-57-1)
• EPA Substance Registry System: 5-methylpyridine-3-sulfonyl chloride(166337-57-1)

Safety Data

• Hazardous Substances Data: 166337-57-1(Hazardous Substances Data)

Upstream product

• 4808-70-2 5-methylpyridine-3-sulfonic acid 
• 3430-16-8 5-bromo-3-picoline 
• 1210868-05-5 3-(benzylsulfanyl)-5-methylpyridine 

Downstream Products

• 4808-70-2 5-methylpyridine-3-sulfonic acid 

Relevant articles and documents

Utilizing Carbonyl Coordination of Native Amides for Palladium-Catalyzed C(sp3)?H Olefination

PdII-catalyzed C(sp3)?H olefination of weakly coordinating native amides is reported. Three major drawbacks of previous C(sp3)?H olefination protocols, 1) in situ cyclization of products, 2) incompatibility with α-H-containing substrates, and 3) installation of exogenous directing groups, are addressed by harnessing the carbonyl coordination ability of amides to direct C(sp3)?H activation. The method enables direct C(sp3)?H functionalization of a wide range of native amide substrates, including secondary, tertiary, and cyclic amides, for the first time. The utility of this process is demonstrated by diverse transformations of the olefination products.

PYRROLE COMPOUNDS

The present invention relates to a compound represented by the formula: wherein A is pyridyl group having at least one substituent wherein R1, R2 and R3 are each a hydrogen atom, a halogen atom, a C1-6 alkyl group optionally substituted by halogen or a C1-6 alkoxy group optionally substituted by halogen, R4 and R6 are each a hydrogen atom, a halogen atom or a C1-6 alkyl group optionally substituted by halogen, R5 is a hydrogen atom, a halogen atom, a C1-6 alkyl group optionally substituted by halogen or a C1-6 alkoxy group optionally substituted by halogen, and R7 is a hydrogen atom or a C1-6 alkyl group optionally substituted by halogen or a salt thereof, or a pharmaceutical composition containing the same.