1663512-03-5Relevant academic research and scientific papers
Ru-catalyzed branched versus linear selective C3-alkylation of 2-aroylbenzofurans with acrylates via C-H activation
Kommagalla, Yadagiri,Srinivas, Kolluru,Ramana, Chepuri V.
supporting information, p. 7884 - 7889 (2014/07/07)
The carbonyl-directed C3-H activation and alkylation of 2-aroylbenzo[b]furans with acrylates occurs selectively either in a linear or branched fashion, depending on the catalyst employed; [Ru(p-cymene)Cl 2]2 or Ru(PPh3)3Cl2, respectively. Two alternate pathways - funded upon the differences in steric and electronic preferences of these two complexes - is proposed for the selectivity of linear versus branched products. Branched-selective alkylation with acrylates has been cracked: Catalyst-dependent branched versus linear alkylation of benzofuran with acrylate has been established. [Ru(PPh3) 3Cl2] produces unusual branched-selective, alkylated adducts as major products, whereas [Ru(p-cymene)Cl2]2 selectively gives the linear, alkylated benzofuran adducts as major products (see scheme).
