166406-79-7

Upstream product

• 135-77-3 1,2,4-trimethoxy-benzene 
• 39052-34-1 11-bromo-8-drimene 
• 124377-31-7 (+)-[(4aS,8aS)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]methanol 
• 59684-77-4 (1R,4aS,8aS)-3,4,4a,5,6,7,8,8a-octahydro-1-methoxycarbonyl-5,5,8a-trimethyl-trans-naphthalene-2(1H)-one 

Relevant academic research and scientific papers

Natural product synthesis from (8aR)- and (8aS)-bicyclofarnesols: synthesis of (+)-wiedendiol A, (+)-norsesterterpene diene ester and (-)-subersic acid

Both enantiomers (8aR)-7 and (8aS)-7 of bicyclofarnesol were synthesized from the enzymatic resolution products (1R,4aR,8aR)-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-trimethyl-2-oxo-trans-naphthalene-1-methanol-2-ethylene acetal (8aR)-5 (98% ee) and acetate

An Efficient Synthesis of Wiedendiol-A from (+)-Sclareolide

An efficient synthesis of Wiedendiol-A (1) is described starting from commercially available (+)-sclareolide.This synthesis also confirms the absolute stereochemistry of Wiedendiol-A.