16643-41-7

Usage

Uses

Used in Pharmaceutical Industry:
2,4-diphenylbicyclo[3.3.1]non-2-en-9-one is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-diphenylbicyclo[3.3.1]non-2-en-9-one is utilized as a precursor in the production of agrochemicals. Its incorporation into these compounds can enhance their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Medicinal Chemistry Research:
2,4-diphenylbicyclo[3.3.1]non-2-en-9-one is also employed as a subject of study in medicinal chemistry. Its interesting reactivity and structural features have attracted the attention of researchers, who are exploring its potential applications in the discovery and development of novel therapeutic agents.

Upstream product

• 2682-98-6 2-(3-oxo-1,3-diphenylpropyl)cyclohexanone 

Downstream Products

• 1107692-77-2 1,2,3,5-tetrachloro-2,4-diphenylbicyclo[3.3.1]nonan-9-one 
• 1107692-78-3 2,3-dibromo-2,4-diphenylbicyclo[3.3.1]nonan-9-one 
• 13116-65-9 2exo,4exo-diphenyl-bicyclo[3.3.1]nonan-9-one 
• 13116-65-9 (+/-)-2endo,4exo-diphenyl-bicyclo[3.3.1]nonan-9-one 

Relevant academic research and scientific papers

Chemistry of 1,5-diketones: II. Specificity of transformations of polycyclic 1,5-diketones in acid media

2-(1,3-Diaryl-3-oxopropyl)cyclohexan-1-ones underwent carbo-and heterocyclization in a mixture of acetic acid with acetic anhydride in the presence of perchloric acid. The transformation of 2-(1,3-diaryl-3-oxopropyl) cyclohexan-1-ones into 2,4-diaryl-5,6,7,8-tetrahydrochromenylium salts was shown to involve intermediate 2,4-diarylbicyclo[3.3.1]non-2-en-9-ones. The structure of 2,4-diaryl-substituted bicyclo[3.3.1]non-2-en-9-ones and products of their reactions with halogens and hydroxylamine hydrochloride was confirmed by 1H and 13C NMR spectroscopy.

Chemiluminescent 1,2-dioxetanes

A method of generating light through chemiluminescence involves providing a stable 1,2-dioxetane of the formula: Wherein (a) R1 and R2 are each, individually, a chemical reactive site or when fused together form a chemical reactive site, and R3 and R4 are each, individually, a chemical reactive site or when fused together form a chemical reactive or (b) R1 has at least two hetero atoms with chemical reactive site and R3 and R4 are inactive site and R2 is a chemical reactive site.

Chemiluminescent 1,2-dioxetanes

A method of generating light through chemiluminescence involves providing a stable 1,2-dioxetane of the formula: Wherein (a) R1 and R2 are each, individually, a chemical reactive site or when fused together form a chemical reactive site, and R3 and R4 are each, individually, a chemical reactive site or when fused together form a chemical reactive or (b) R1 has at least two hetero atoms with chemical reactive site and R3 and R4 are inactive site and R2 is a chemical reactive site.

Chemiluminescent 1,2-dioxetanes

The present invention provides novel 1,2-dioxetanes derived from spiro-fused ketones with or without π-electrons in the ring or with carbon-carbon double bond(s) in the spiro-fused ring. Additionally, these new dioxetanes have electron donating or withdrawing groups at the four-membered peroxide ring to render these dioxetanes active at all sites.

Synthesis and Structure of Phenyl-Substituted Bicyclononenes

Addition of one mole of phenyllithium to bicyclononane-2,6-dione (5) affords the hydroxy ketone 6 besides small amounts of the known diol 7.Dehydration of this mixture by sulfuric acid in acetic acid yields the unsaturated ketone 8 and the diene 1 which are separated by chromatography.Wolff-Kishner reduction of 8 furnished the hydrocarbon 2.In the same way, the known ketones exo- and endo-10 are converted into 4.The preferential formation of the less stable endo-10 is interpreted in terms of the relative stability of the conformations required in the intramolecular aldol reaction of diketone 9.The conformations of 4, 8, exo- and endo-10 are determined by X-ray diffraction analyses.Vicinal proton coupling constants are calculated from torsional anlges and compared to those determined in solutions by high-field NMR spectroscopy.Key Words: Bicyclonon-2-ene, phenyl-substituted derivatives of / Conformation of bicyclonon-2-enes