166451-20-3

Upstream product

• 34897-85-3 o-azidobenzoyl chloride 
• 31162-13-7 2-azidobenzoic acid 
• 32968-78-8 (2S,4R)-4-hydroxy-2-pyrrolidinecarboxylic acid hydrochloride 

Downstream Products

• 166451-21-4 ethyl (2S,4R)-N-(2-azidobenzoyl)-4-hydroxypyrrolidine-2-carboxylate 
• 1016557-19-9 C₁₄H₁₇N₅O₄ 

Relevant academic research and scientific papers

A facile intramolecular azido/amido reductive cyclization approach: synthesis of pyrrolobenzodiazepines and their dimers

A new synthetic pathway has been developed for the preparation of imine-containing pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) and their dimers. Selective reduction of aromatic azides as well as aliphatic amides in a single step leading to an intramolecular

Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines via an intramolecular aza-Wittig reaction. Synthesis of the antibiotic DC-81

A new and efficient synthesis of the pyrrolo[2,1-c][1,4]benzodiazepine ring system has been carried out using, as a key step, an intramolecular aza-Wittig reaction of the appropriately substituted N-(2-azidobenzoyl)pyrrolidine-2-carboxaldehydes. The paren