1665-95-8

Basic information

• Product Name: N-(4-formylphenyl)-N,4-dimethylbenzenesulfonamide
• Synonyms: N-(4-formylphenyl)-N,4-dimethylbenzenesulfonamide
• CAS NO: 1665-95-8
• Molecular Weight: 289.355
• Mol File: 1665-95-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-formylphenyl)-N,4-dimethylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-formylphenyl)-N,4-dimethylbenzenesulfonamide(1665-95-8)
• EPA Substance Registry System: N-(4-formylphenyl)-N,4-dimethylbenzenesulfonamide(1665-95-8)

Safety Data

• Hazardous Substances Data: 1665-95-8(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 640-61-9 N-methyl-p-toluenesulfonylamide 

Downstream Products

• 556-21-8 4-(methylamino)benzaldehyde 

Relevant articles and documents

Chemoselective Deprotection of Sulfonamides under Acidic Conditions: Scope, Sulfonyl Group Migration, and Synthetic Applications

Chemoselective acidic hydrolysis of sulfonamides with trifluoromethanesulfonic acid has been evaluated as a deprotection method and further extended to more complex synthetic applications. In contrast to conventional troublesome sulfonamide hydrolysis, a near-stoichiometric amount of acid was found to be sufficient to bring about efficient deprotection of various neutral or electron-deficient N-arylsulfonamides, whereas electron-rich substrates provided sulfonyl group migration products. The deprotection method developed is fully selective for N-arylsulfonamides, and the possibility to discriminate among various different sulfonamides is demonstrated.