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16655-90-6

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16655-90-6 Usage

General Description

DL-2-Indanylglycine, also known as DL-2-(1H-Inden-2-yl)glycine, is a synthetic heterocyclic aromatic chemical compound. Not much information is available about this specific compound, but it likely has properties similar to other indanylglycines, which are typically used in pharmaceuticals. Indanylglycines as a whole are known to interact with certain neurotransmitter systems in the body, particularly the glycine site of the NMDA receptor. Some indanylglycines have been studied for their potential role in the treatment of neurological conditions, but more research would be needed to determine the exact uses and properties of DL-2-Indanylglycine.

Check Digit Verification of cas no

The CAS Registry Mumber 16655-90-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,5 and 5 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 16655-90:
(7*1)+(6*6)+(5*6)+(4*5)+(3*5)+(2*9)+(1*0)=126
126 % 10 = 6
So 16655-90-6 is a valid CAS Registry Number.

16655-90-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name DL-2-Indanylglycine

1.2 Other means of identification

Product number -
Other names rac-Homoormosanin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16655-90-6 SDS

16655-90-6Relevant articles and documents

2,5-Diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 2. Synthesis, chirality, and pharmacokinetics

Borthwick, Alan D.,Davies, Dave E.,Exall, Anne M.,Livermore, David G.,Sollis, Steve L.,Nerozzi, Fabrizio,Allen, Michael J.,Perren, Marion,Shabbir, Shalia S.,Woollard, Patrick M.,Wyatt, Paul G.

, p. 6956 - 6969 (2007/10/03)

A short stereoselective synthesis of a series of chiral 7-aryl-2,5-diketopiperazines oxytocin antagonists is described. Varying the functionality and substitution pattern of substituents in the 7-aryl ring and varying the chirality of this exocyclic ring have produced potent oxytocin antagonists (pKi > 8.5). SAR and pharmacokinetic profiling of this series of (3R,6R,7R)-2,5-diketopiperazines together with the introduction of an ortho F group in the 7-aryl ring to improve rat pK has culminated in the 2′,4′-difluorophenyldiketopiperazine derivative 37, a highly potent oxytocin antagonist against the human oxytocin receptor (pKi = 8.9) that has > 1000-fold selectivity over all three vasopressin receptors V1a, V2, and V1b. It has good bioavailability (46%) in the rat and moderate bioavailability (13-31%) in the dog and is more active in vivo in the rat than atosiban (rat DR10 = 0.44 mg/kg iv).

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