166672-54-4

Upstream product

• 130669-75-9 (3aS,7aS)-4-bromo-2,2-dimethyl-3a,7a-dihydro-1,3-benzodioxole 
• 15777-88-5 dimetilamide dell'acido 3,4-metilendiossibenzoico 
• 183902-27-4 (3aS,4S,5R,7aS)-5-Azido-7-bromo-2,2-dimethyl-3a,4,5,7a-tetrahydro-benzo[1,3]dioxol-4-ol 
• 67451-62-1 cis-(1S,2S)-1,2-dihydroxy-3-bromocyclohexa-3,5-diene 
• 100-39-0 benzyl bromide 
• 163082-11-9 methyl 6-<(1R,4R,5S,6R)-6-<(tert-butyloxycarbonyl)amino>-4,5-(isopropylidenedioxy)-2-cyclohexen-1-yl>-4-(phenylmethoxy)-1,3-benzodioxole-5-carboxylate 
• 181698-30-6 N,N-dimethyl-4-hydroxy-1,3-benzodioxole-5-carboxamide 
• 183674-17-1 (1R,2S,5S,6R)-3,6-dibromo-1,2-O-isopropylidenecyclohex-3-ene-1,2,5-triol 
• 160309-18-2 (1R,4R,5S,6R)-4,5-(isopropylidenedioxy)-7-(4'-methylphenylsulfonyl)-7-azabicyclo<4.1.0>hept-2-ene 
• 163082-14-2 N,N-dimethyl-4-<(tert-butyldimethylsilyl)oxy>-6-<(1R,4R,5S,6R)-6->-4,5-(isopropylidenedioxy)-2-cyclohexen-1-yl>-1,3-benzodioxole-5-carboxamide 
• 163082-06-2 N,N-dimethyl-4-<(tert-butyldimethylsilyl)oxy>-6-<(1R,4R,5S,6R)-4,5-(isopropylidenedioxy)-6-<(4'-methylphenylsulfonyl)amino>-2-cyclohexen-1-yl>-1,3-benzodioxole-5-carboxamide 
• 163082-07-3 N,N-dimethyl-6-<(1R,4R,5S,6R)-4-(tert-butyldimethylsilyl)-6-<(tert-butyloxycarbonyl)amino>-4,5-(isopropylidenedioxy)-2-cyclohexen-1-yl>-1,3-benzodioxole-5-carboxamide 
• 163082-10-8 (3'aS,4'R,5'R,7'aR)-7-Benzyloxy-4'-tert-butoxycarbonylamino-2',2'-dimethyl-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid 
• 163082-09-5 6-<(1R,4R,5S,6R)-6-<(tert-butyloxycarbonyl)amino>-4,5-(isopropylidenedioxy)-2-cyclohexen-1-yl>-4-(phenylmethoxy)-1,3-benzodioxole-5-carbaldehyde 

Downstream Products

• 96203-70-2 pancratistatin 
• 163082-12-0 methyl 6-<(1R,2R,3S,4S,5S,6R)-6-<(tert-butyloxycarbonyl)amino>-5,6-epoxy-3,4-dihydroxycyclohex-1-yl>-4-(phenylmethoxy)-1,3-benzodioxole-5-carboxylate 

Relevant academic research and scientific papers

Synthesis of (+)-pancratistatin

This is described an improved process for the asymetric synthesis of (+)-Pancratistatin utilizing aziridines as the starting materials.

Toluene dioxygenase-mediated cis-dihydroxylation of aromatics in enantioselective synthesis. Asymmetric total syntheses of pancratistatin and 7-deoxypancratistatin, promising antitumor agents

Whole-cell biooxidation of bromobenzene with Pseudomonas putida 39D or the recombinant Escherichia coli JM109 (pDTG601) yields (1S,2S)-3-bromocyclohexa-3,5-diene-1,2-diol (9a), which is protected as the acetonide and converted to vinylaziridines 7, 15a, 6