(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2'-oxiran]-3-ol, commonly known as Spironolactone, is a synthetic steroid and potassium-sparing diuretic medication. It functions by inhibiting the effects of aldosterone, a hormone that controls the body's salt and water balance. This medication is utilized for various therapeutic purposes, including the management of fluid retention and high blood pressure.
16669-01-5
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Basic information
- Product Name: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a] phenanthrene-17,2'-oxiran]-3-ol
- Synonyms:
- CAS NO:16669-01-5
- Molecular Formula:
- Molecular Weight: 284.398
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a] phenanthrene-17,2'-oxiran]-3-ol(CAS DataBase Reference)
- NIST Chemistry Reference: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a] phenanthrene-17,2'-oxiran]-3-ol(16669-01-5)
- EPA Substance Registry System: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a] phenanthrene-17,2'-oxiran]-3-ol(16669-01-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 16669-01-5(Hazardous Substances Data)
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16669-01-5 Usage
Uses
Used in Pharmaceutical Industry:Spironolactone is used as a diuretic agent for treating fluid retention (edema) in patients with congestive heart failure, cirrhosis of the liver, or nephrotic syndrome, a kidney disorder. Its ability to spare potassium while promoting the excretion of sodium and water makes it a valuable treatment option for these conditions.
Additionally, Spironolactone is used as an antihypertensive agent for managing high blood pressure. Its diuretic effect helps in reducing blood volume, which in turn lowers blood pressure.
Furthermore, Spironolactone may be prescribed for other medical conditions as determined by a healthcare professional, showcasing its versatility in pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 16669-01-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,6 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.Calculate Digit Verification of CAS Registry Number 16669-01:
(7*1)+(6*6)+(5*6)+(4*6)+(3*9)+(2*0)+(1*1)=125
125 % 10 = 5
So 16669-01-5 is a valid CAS Registry Number.
16669-01-5Upstream product
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(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a] phenanthrene-17,2'-oxiran]-3-ol
