16675-74-4Relevant academic research and scientific papers
1,2-Dihydroisoquinolines. XXII. Benzoquinolizine Derivatives
Dyke, Stanley F.,Spray, Clive R.,Kilminster, Raymond A.
, p. 149 - 155 (2007/10/02)
Some time ago it was reported that 4,6,11,11a-tetrahydro-1H-benzoquinolizin-2(3H)-ones are produced when N-benzylaminoacetaldehyde dialkyl acetals react with methyl vinyl ketone in acid solution.These structures have now been confirmed, the scope of the reaction broadened and the conformations of the products investigated.Some of these ketones have been treated with phenylmagnesium bromide, but no useful central nervous system activity has been found for any of the tertiary alcohols produced.
