166751-32-2

Basic information

• Product Name: 4(1H)-Pyrimidinone, 6-amino-2-[[(2,6-difluorophenyl)methyl]thio]-
• CAS NO: 166751-32-2
• Molecular Formula: C11H9F2N3OS
• Molecular Weight: 269.275
• Mol File: 166751-32-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4(1H)-Pyrimidinone, 6-amino-2-[[(2,6-difluorophenyl)methyl]thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 6-amino-2-[[(2,6-difluorophenyl)methyl]thio]-(166751-32-2)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 6-amino-2-[[(2,6-difluorophenyl)methyl]thio]-(166751-32-2)

Safety Data

• Hazardous Substances Data: 166751-32-2(Hazardous Substances Data)

Upstream product

• 85118-00-9 2,6-Difluorobenzyl bromide 
• 65802-56-4 4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate 
• 1004-40-6 4-aminothiouracil 

Relevant articles and documents

Pyrimidine-thioalkyl and alkylether compounds

The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula I and pyrimidine-thioalkyl and alkylethers of Formula IA, namely the compounds of Formula I whereR4 is selected from the group consisting of -H or -NRsub

Pyrimidine-thioalkyl and alkylether compounds

The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula (I) and pyrimidine-thioalkyl and alkylethers of Formula (IA), namely the compounds of Formula (I) where R 4 is selected from the group consisting of --H or --NR 15 R 16 where R 15 is --H and R 16 is --H, C 1 -C 6 alkyl, --NH 2 or R 15 and R 16 taken together with the --N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and R 6 is selected from the group consisting of --H, or halo (preferably --Cl); with the overall proviso that R 4 and R 6 are not both --H. The compounds of Formula (IA) are useful in the treatment of individuals who are HIV positive.