166755-08-4Relevant academic research and scientific papers
Novel Inhibitors of the Nuclear Factor of Activated T Cells (NFAT)-Mediated Transcription of β-Galactosidase: Potential Immunosupressive and Antiinflammatory Agents
Michne, William F.,Schroeder, Joseph D.,Guiles, Joseph W.,Treasurywala, Adi M.,Weigelt, Carolyn A.,et al.
, p. 2557 - 2569 (2007/10/02)
The preparation of a series of quinazoline-2,4-diones, 1-3, and pyrrolopyrimidine-2,4-diones, 4-8 is described.A small number of quinazolinedione analogs were identified from random screening to possess low micromolar (1.3-4.4 μM) potency in the nu
