166760-75-4Relevant academic research and scientific papers
Inhibition of monoamine oxidase-b by 5H-indeno[1,2-c]pyridazines: Biological activities, quantitative structure-activity relationships (QSARs) and 3D-QSARs
Kneubuhler,Thull,Altomare,Carta,Gaillard,Carrupt -,Carotti,Testa
, p. 3874 - 3883 (2007/10/03)
A large series (66 compounds) of indeno[1,2-c]pyridazin-5-ones (IPs) were synthesized and tested on their monoamine oxidase-A (MAO-A) and MAO-B inhibitory activity. All of the tested compounds acted preferentially on MAO- B displaying weak (nonmeasurable
