16681-69-9

Basic information

• Product Name: 1-Methyl-1H-1,2,3-triazole-4-carbaldehyde
• Synonyms: 1-Methyl-1H-1,2,3-triazole-4-carbaldehyde;1H-1,2,3-triazole-4-carboxaldehyde, 1-methyl-
• CAS NO: 16681-69-9
• Molecular Formula: C₄H₅N₃O
• Molecular Weight: 111.102
• Product Categories: Intermediates
• Mol File: 16681-69-9.mol
• Article Data: 10

Chemical Properties

• Melting Point: 113-113.5 °C
• Boiling Point: 253.5±32.0 °C(Predicted)
• Appearance: /
• Density: 1.31±0.1 g/cm3(Predicted)
• PKA: -0.79±0.10(Predicted)
• CAS DataBase Reference: 1-Methyl-1H-1,2,3-triazole-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-1H-1,2,3-triazole-4-carbaldehyde(16681-69-9)
• EPA Substance Registry System: 1-Methyl-1H-1,2,3-triazole-4-carbaldehyde(16681-69-9)

Safety Data

• Hazardous Substances Data: 16681-69-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 27, p. 2021, 1990 DOI: 10.1002/jhet.5570270733

Upstream product

• 77177-21-0 (1-methyl-1H-[1,2,3]triazol-4-yl)methanol 
• 151918-33-1 Methyl-[1-[1,2,3]thiadiazol-4-yl-meth-(E)-ylidene]-amine 
• 513-81-5 2,3-dimethyl-buta-1,3-diene 
• 133902-56-4 [1-(1-Methyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-phenyl-amine 
• 129027-59-4 [1-(1-Methyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-phenyl-amine 
• 624-67-9 Propargylic aldehyde 
• 624-90-8 methyl azide 

Downstream Products

• 1207454-72-5 ethyl 2-(4-fluorophenyl)-3-(1-methyl-1H-1,2,3-triazol-4-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 114488-58-3 p-Methoxybenzyl (5R) 6-(1-methyl-1,2,3-triazol-4-ylmethylene)penem-3-carboxylate 
• 16681-71-3 1-methyl-1H-1,2,3-triazole-4-carboxylic acid 

Relevant articles and documents

3-CARBOXYLIC ACID PYRROLES AS NRF2 REGULATORS

The present invention relates to 3-carboxylic acid pyrrole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators. In particular, the compounds of this invention include a compound of Formula (I)

ARYLCYCLOHEXYL PYRAZOLES AS NRF2 REGULATORS

The present invention relates to arylcyclohexyl pyrazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.

A polymorphism-dependent T1/2 shift of 100 K in a hysteretic spin-crossover complex related to differences in intermolecular weak CH?X hydrogen bonds (X = S vs. S and N)

A neutral mononuclear iron(ii) complex with a 1,2,3-triazole-containing tetradentate ligand has been obtained as two solvent-free polymorphs. Both polymorphs show hysteretic spin crossover with a polymorphism-dependent T1/2 shift of 100 K that