166812-65-3

Upstream product

• 29968-78-3 2-(4-nitrophenyl)ethylamine monohydrochloride 
• 86447-66-7 2,5-anhydro-3-deoxy-4,6-di-O-toluoyl-D-ribohexose 
• 86447-65-6 2-(2'-deoxy-3',5'-di-O-toluoyl-β-D-ribofuranosyl)-1,3-diphenylimidazolidine 
• 50908-41-3 2,5-anhydro-3-deoxy-4,6-di-O-toluoyl-D-ribohexononitrile 

Downstream Products

• 166812-66-4 5-(2'-deoxy-3',5'-di-O-toluoyl-β-D-ribofuranosyl)-1-<2-(4-nitrophenyl)ethyl>-1H-imidazole-2-carbonitrile 
• 166812-67-5 5-(2'-deoxy-3',5'-di-O-toluoyl-β-D-ribofuranosyl)-1-<2-(4-nitrophenyl)ethyl>-1H-imidazole-2-carboxamide 

Relevant academic research and scientific papers

Synthesis of 2'-Deoxy-&β-D-ribofuranosyl Imidazole and Thiazole C-Nucleosides

A synthetic route to 2-carbamoyl-4-(2'-deoxy-β-D-ribofuranosyl)imidazole 3, starting from 2-deoxy-3,5-di-O-toluoyl-β-D-ribofuranosyl cyanide 4, was developed.The key steps are reduction of the cyano group of compound 4 to a formyl and subsequent condensat