166819-07-4Relevant academic research and scientific papers
Synthesis, Structure Elucidation, and Biochemical Evaluation of 7α- and 7β-Arylaliphatic-Substituted Androst-4-ene-3,17-diones as Inhibitors of Aromatase
O'Reilly, Jill M.,Li, Naiyin,Duax, William L.,Brueggemeier, Robert W.
, p. 2842 - 2850 (2007/10/02)
The inhibition of aromatase, the cytochrome P450 enzyme complex responsible for the conversion of androgens to estrogens, may be useful for the endocrine treatment of breast cancer.Previously, several 7α-thio-substituted androstenediones have been shown t
