166941-47-5

Basic information

• Product Name: (S)-(-)-2-T-BUTYL-2-PIPERAZINECARBOXAMIDE
• Synonyms: S-BPCA;(S)-PIPERAZINE-2-CARBOXYL-T-BUTYLAMIDE;(S)-PIPERAZINE-2-CARBOXYL-TERT-BUTYLAMIDE;(S)-PIPERAZINE-2-CARBOXY-T-BUTYLAMIDE;(S)-2-(T-BUTYLCARBOXAMIDO) PIPERAZINE;(S)-(-)-2-T-BUTYL-2-PIPERAZINECARBOXAMIDE;(S)-2-PIPERAZINE-TERT-BUTYL-CARBOXAMIDE;(R)-PIPERAZINE-2-CARBOXY-T-BUTYLAMIDE
• CAS NO: 166941-47-5
• Molecular Formula: C₉H₁₉N₃O
• Molecular Weight: 185.27
• Product Categories: PIPERIDINE
• Mol File: 166941-47-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 368.204 °C at 760 mmHg
• Flash Point: 156.12 °C
• Appearance: /
• Density: 0.985 g/cm³
• Refractive Index: 1.477
• PKA: 16.10±0.20(Predicted)
• CAS DataBase Reference: (S)-(-)-2-T-BUTYL-2-PIPERAZINECARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-2-T-BUTYL-2-PIPERAZINECARBOXAMIDE(166941-47-5)
• EPA Substance Registry System: (S)-(-)-2-T-BUTYL-2-PIPERAZINECARBOXAMIDE(166941-47-5)

Safety Data

• Hazardous Substances Data: 166941-47-5(Hazardous Substances Data)

Usage

Description

(S)-(-)-2-T-BUTYL-2-PIPERAZINECARBOXAMIDE, a chemical compound with the molecular formula C11H22N2O and a molecular weight of 198.31 g/mol, is classified under chiral building blocks, piperazines, and pharmaceutical intermediates. It exhibits optical rotation of -46 (c=1, MeOH) and is primarily utilized in the pharmaceutical industry. Its exact applications are still under research and exploration.

Uses

Used in Pharmaceutical Industry:
(S)-(-)-2-T-BUTYL-2-PIPERAZINECARBOXAMIDE is used as a pharmaceutical intermediate for the development of new drugs and medications. Its role in this industry is to serve as a building block in the synthesis of various pharmaceutical compounds, contributing to the creation of potential therapeutic agents.
It is important to handle and store (S)-(-)-2-T-BUTYL-2-PIPERAZINECARBOXAMIDE appropriately in laboratory or industrial settings to maintain its stability and prevent any potential danger or dysfunction. As research progresses, further applications and uses of this compound may be discovered, expanding its utility in the pharmaceutical field and potentially other industries.

InChI:InChI=1/C9H19N3O/c1-8(2,3)9(7(10)13)6-11-4-5-12-9/h11-12H,4-6H2,1-3H3,(H2,10,13)/t9-/m0/s1

Upstream product

• 121885-10-7 pyrazinecarboxylic acid tert-butylamide 

Downstream Products

• 189349-50-6 L-765314 
• 189349-69-7 (S)-4-[(benzyloxy)carbonyl]-3-(1,1-dimethylethylamino) carbonyl piperazine 
• 150323-35-6 t-butyl (S)-3-(tert-butylcarbamoyl)-piperazine-1-carboxylate 

Relevant articles and documents

Process for the preparation of optically active piperazine-2-carboxylic acid derivatives

Optically active piperazine-2-carboxylic acid derivatives of the general formula: STR1 in which X is alkoxy or a (substituted) amino group, are prepared by asymmetric hydrogenation of the corresponding pyrazinecarboxylic acid derivatives, catalyzed by optically active rhodium complexes. The compounds of the formula I are intermediates for the preparation of pharmaceutical active substances, for example, HIV protease inhibitors.