167010-31-3

Upstream product

• 167010-30-2 N-((5S)-3-(3,5-Difluorophenyl)-2-oxooxazolidin-5-ylmethyl)acetamide 

Downstream Products

• 882185-06-0 N-({(5S)-3-[3,5-difluoro-4-(trimethylstannyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide 
• 883231-27-4 N-[((5S)-2-oxo-3-{2,3',6-trifluoro-4'-[(E)-(hydroxyimino)methyl]biphenyl-4-yl}-1,3-oxazolidin-5-yl)methyl]acetamide 
• 1188917-87-4 (S,S)-N-{3-[2,6-difluoro-4'-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxymethyl)-biphenyl-4-yl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 

Relevant academic research and scientific papers

OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS

The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

Antibiotic oxazolidinone derivatives

The invention concerns a compound of the formula (I): wherein, for example:T is of the formula (IA), (IB), or (IC); R1 is of the formula —NHC(=O)Rb wherein Rb is (1-4C)alkyl;R2 and R3 are hydrogen or