167015-23-8Relevant articles and documents
Fluorinated and iodinated templates for syntheses of β-turn peptidomimetics
Jiang, Luyong,Burgess, Kevin
, p. 8743 - 8750 (2007/10/03)
Various 2-fluoro-5-nitrobenzoic acids and the homocysteine derivative 2 have been combined in solid phase syntheses of the peptidomimetic types 3-6. NMR and CD data collected for some of these compounds indicate that a transannular SO to HN hydrogen bond stabilizes β-turn conformations for the sulfones and one of the sulfoxide epimers. An extensive library of compounds was made and studied to test this assertion.