Azido-PEG9-acid is a PEG molecule that features an azide group and a terminal carboxylic acid. The hydrophilic PEG spacer enhances its solubility in aqueous environments, while the azide group is capable of reacting with alkyne, BCN, and DBCO through Click Chemistry, resulting in a stable triazole linkage. The terminal carboxylic acid can also react with primary amine groups when activators such as EDC or HATU are present.
1670249-37-2
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Basic information
- Product Name: Azido-PEG9-acid
- Synonyms: Azido-PEG9-acid;N3-PEG9-CH2CH2COOH;N3-PEG9-COOH
- CAS NO:1670249-37-2
- Molecular Formula: C21H41N3O11
- Molecular Weight: 511.56374
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1670249-37-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Soluble in Water, DMSO, DCM, DMF
- CAS DataBase Reference: Azido-PEG9-acid(CAS DataBase Reference)
- NIST Chemistry Reference: Azido-PEG9-acid(1670249-37-2)
- EPA Substance Registry System: Azido-PEG9-acid(1670249-37-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1670249-37-2(Hazardous Substances Data)
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1670249-37-2 Usage
Uses
Used in Bioconjugation:Azido-PEG9-acid is used as a bioconjugation agent for attaching biomolecules to other molecules or surfaces. The azide group facilitates the formation of stable triazole linkages through Click Chemistry, enabling the efficient and specific attachment of various biomolecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Azido-PEG9-acid is used as a component in drug delivery systems to improve the solubility, stability, and targeted delivery of therapeutic agents. The hydrophilic PEG spacer and terminal carboxylic acid allow for the attachment of drugs and other functional groups, enhancing the overall performance of the drug delivery system.
Used in Diagnostic Imaging:
Azido-PEG9-acid is utilized as a component in diagnostic imaging agents, where its ability to form stable triazole linkages through Click Chemistry allows for the attachment of imaging probes or contrast agents to biomolecules or nanoparticles, improving the sensitivity and specificity of imaging techniques.
Used in Material Science:
In the field of material science, Azido-PEG9-acid is used as a building block for the development of functional materials with tailored properties. The azide group and terminal carboxylic acid enable the formation of complex structures and networks through Click Chemistry, allowing for the creation of materials with specific characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1670249-37-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,7,0,2,4 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.Calculate Digit Verification of CAS Registry Number 1670249-37:
(9*1)+(8*6)+(7*7)+(6*0)+(5*2)+(4*4)+(3*9)+(2*3)+(1*7)=172
172 % 10 = 2
So 1670249-37-2 is a valid CAS Registry Number.
1670249-37-2Upstream product
1670249-37-2Downstream Products
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Azido-PEG9-acid
