167083-91-2

Upstream product

• 167083-90-1 (4R,5S)-2,2-Dimethyl-5-((2S,3S,4S,5R,6S)-3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-yl)-[1,3]dioxolane-4-carboxylic acid 
• 19493-09-5 Methylenetriphenylphosphorane 
• 125287-98-1 methyl [methyl 2,3,4-tri-O-benzyl-L-threo-β-D-gluco-octopyranosid]uronate 
• 167083-89-8 (4R,5S)-2,2-Dimethyl-5-((2S,3S,4S,5R,6S)-3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-yl)-[1,3]dioxolane-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Application of stabilized sugar-derived phosphoranes in the synthesis of higher carbon monosaccharides. First synthesis of a C21-dialdose

C21 Monosaccharide precursors 11 and 12 were synthesized by a coupling of a C12 aldehyde 1 with C9 stabilized phosphoranes 2 and 3 respectively. The 'smaller' C19 sugar 13 was prepared from a C12 alde

Synthesis of derivatives of C19 and C21 dialdoses

C12-monosaccharide derivative 2 (obtained from C12-dialdose 1 in 49% overall yield) was used as the starting material for the preparation of C19- and C21-monosaccharide derivatives. Coupling of aldehyde 3 (prepa