16709-66-3

Basic information

• Product Name: Benzoic acid, 4-chloro-, 2-oxo-2H-1-benzopyran-4-yl ester
• Synonyms: 2-oxo-2H-chromen-4-yl 4-chlorobenzoate
• CAS NO: 16709-66-3
• Molecular Formula: C16H9ClO4
• Molecular Weight: 300.69
• Mol File: 16709-66-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 4-chloro-, 2-oxo-2H-1-benzopyran-4-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-chloro-, 2-oxo-2H-1-benzopyran-4-yl ester(16709-66-3)
• EPA Substance Registry System: Benzoic acid, 4-chloro-, 2-oxo-2H-1-benzopyran-4-yl ester(16709-66-3)

Safety Data

• Hazardous Substances Data: 16709-66-3(Hazardous Substances Data)

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 122-01-0 4-chloro-benzoyl chloride 

Relevant articles and documents

Inhibition of reverse transcriptase and Taq DNA polymerase by compounds possessing the coumarin framework

Coumarin derivatives were prepared using natural products isolated from plants belonging in the Pterocaulon genus (Asteraceae) and commercial drugs. Some molecules have displayed interesting activity against myeloid murine leukemia virus-reverse transcriptase (MMLV-RT) (compounds 20 and 28 produced inhibition with IC50 values of 38.62 and 50.98 μM, respectively) and Taq DNA polymerase (analogues 13 and 14 produced inhibition with IC 50 values of 48.08 and 57.88 μM, respectively). Such inhibitors may have importance as antiretroviral chemotherapeutic agents and also in the development of anticancer drugs.