167101-77-1Relevant academic research and scientific papers
Asymmetric Synthesis of (2R,5S,7R)-2,7-Dimethyl-1,6-dioxaspirononane
Solladie, Guy,Huser, Nathalie,Fischer, Jean,Decian, A.
, p. 4988 - 4990 (1995)
A short enantioselective synthesis of (2R,5S,7R)-2,7-dimethyl-1,6-dioxaspirononane is described via an enantioselective synthesis of (2S,8S,SR)-2,8-dihydroxy-5-(1,3-dioxolanyl)-1,9-(p-tolylsulfinyl)nonane by stereoselective reduction of the corresponding diketo disulfoxide.The formation of the spiro carbon was stereocontrolled during a cyclization carried out under equilibrating conditions in the presence of ZnBr2.
