1672-33-9Relevant academic research and scientific papers
Spontaneous resolution of a triple-stranded dinickel(II) helicate generated via intermolecular transamination reaction of S-methylisothiocarbohydrazide in the presence of Ni2+
Dobrov, Anatoly,Arion, Vladimir B.,Shova, Sergiu,Roller, Alexander,Rentschler, Eva,Keppler, Bernhard K.
, p. 4140 - 4145 (2008)
The reaction of S-methylisothiocarbohydrazide hydroiodide [H 2NNHC(SCH3)NNH2·HI] with NiCl 2·6H2O in water at room temperature yielded a triple-stranded dinickel(II) helicate [NiII(L1-L 1)3NiII]I4·4H2O (14+·4I-·4H2O), where L 1-L1 = H2NNHC(SCH3)NNC(SCH 3)NHNH2, in 35% yield, which spontaneously separates in enantiomers upon crystallization. The enantiomers do not racemize at room temperature, even not after 15 h of heating at 90 °C. X-ray diffraction structures of both enantiomers, chiroptical and magnetic properties of 1 4+·4I-·4H2O are reported. Demetallation of the complex by treatment with S2- resulted in 3,6-bis(methylthio)-1,4-dihydro-1,2,4,5-tetrazine (2). Compound 2 undergoes 2-e- oxidation in air to give the known 3,6-bis(methylthio)-1,2,4,5- tetrazine (3). Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
