167261-47-4

Basic information

• Product Name: 3-(3,4-DICHLOROPHENYL)-1-(3,4,5-TRIMETHOXYBENZOYL)-3-[(3-ACETAMIDO-4-PHENYLPIPERAZIN-1-YL)ETHYL]-PYRROLIDINE
• Synonyms: 3-(3,4-DICHLOROPHENYL)-1-(3,4,5-TRIMETHOXYBENZOYL)-3-[(3-ACETAMIDO-4-PHENYLPIPERAZIN-1-YL)ETHYL]-PYRROLIDINE
• CAS NO: 167261-47-4
• Molecular Formula: C₃₄H₃₉Cl₂N₃O₅
• Molecular Weight: 640.6
• Mol File: 167261-47-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 804.2±65.0 °C(Predicted)
• Appearance: /
• Density: 1.262±0.06 g/cm3(Predicted)
• PKA: 16.05±0.20(Predicted)
• CAS DataBase Reference: 3-(3,4-DICHLOROPHENYL)-1-(3,4,5-TRIMETHOXYBENZOYL)-3-[(3-ACETAMIDO-4-PHENYLPIPERAZIN-1-YL)ETHYL]-PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-DICHLOROPHENYL)-1-(3,4,5-TRIMETHOXYBENZOYL)-3-[(3-ACETAMIDO-4-PHENYLPIPERAZIN-1-YL)ETHYL]-PYRROLIDINE(167261-47-4)
• EPA Substance Registry System: 3-(3,4-DICHLOROPHENYL)-1-(3,4,5-TRIMETHOXYBENZOYL)-3-[(3-ACETAMIDO-4-PHENYLPIPERAZIN-1-YL)ETHYL]-PYRROLIDINE(167261-47-4)

Safety Data

• Hazardous Substances Data: 167261-47-4(Hazardous Substances Data)

Upstream product

• 167262-42-2 2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate 
• 7732-18-5 water 

Relevant articles and documents

CARBOXYSUBSTITUTED CYCLIC CARBOXAMIDE DERIVATIVES

The present invention relates to novel carboxy substituted cyclic carboxamide derivatives of formula (1), STR1 and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, coughs and bronchitis.

SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES

The present invention relates to substituted pyrrolidinyl-3-yl-alkyl-piperidines, their stereoisomers, and pharmaceutically acceptable salts thereof and processes for preparation of the same. The compounds of the present invention are useful in their pharmacological activities such as tachykinin antagonism, especially substance P and neurokinin A antagonism, and the like. Compounds having the property of tachykinin antagonism are indicated for conditions associated with neurogenic inflammation and other diseases described herein.