167389-06-2Relevant academic research and scientific papers
Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents
Sandhu, Harmeet S.,Sapra, Sameer,Gupta, Mukesh,Nepali, Kunal,Gautam, Raju,Yadav, Sunil,Kumar, Raj,Jachak, Sanjay M.,Chugh, Manoj,Gupta, Manish K.,Suri, Om P.,Dhar
, p. 5626 - 5633 (2010)
A series of arylidene analogues of Meldrum's acid were synthesized and evaluated for in vitro antimalarial and antioxidant activities for the first time. The influence of various physico-chemical parameters such as dielectric constant (), donor number (DN
A FACILE EPOXIDATION OF 5-METHYLENE-1,3-DIOXANE-4,6-DIONES WITH HYDROGEN PEROXIDE WITHOUT CATALYST
Tsuno, Takashi,Sugiyama, Kunio,Ago, Hideo
, p. 2631 - 2654 (2007/10/02)
5-Methylene-1,3-dioxane-4,6-diones readily reacted with hydrogen peroxide without any catalyst and any bases to afford the spiro- and poryspirocyclic compounds containing an oxirane ring as good crystalline products.Furthermore, the epoxidation of chiral 5-arylidene-1,3-dioxane-4,6-diones with hydrogen peroxide produced the two diastereomers whose purification by silica gel chromatography ensures 100percent optical purity.
