167422-77-7Relevant academic research and scientific papers
Enantioselective Conjugate Addition of Primary Dialkylzinc Reagents to 2-Aryl- and 2-Heteroaryl-nitroolefins Mediated by Titanium-TADDOLates Preparation of Enantioenriched 2-Aryl-alkylamines
Schaefer, Harald,Seebach, Dieter
, p. 2305 - 2324 (2007/10/02)
The addition of dialkylzinc to nitroolefins is catalyzed by Lewis acids such as MgBr2, MgI2, and chlorotitanates.Using the (R,R)-Ti-TADDOLates the addition of diethyl-, dibutyl-, and dioctyl zinc to 2-aryl-nitroethenes is shown to be enantioselective with
