167468-02-2Relevant articles and documents
Synthesis, modeling, and in vitro activity of (3′S)-epi-K-252a analogues. Elucidating the stereochemical requirements of the 3′-sugar alcohol on trkA tyrosine kinase activity
Gingrich, Diane E.,Yang, Shi X.,Gessner, George W.,Angeles, Thelma S.,Hudkins, Robert L.
, p. 3776 - 3783 (2005)
Utilizing our recently published semisynthetic approach to the (3′S)-K-252a diastereomer, we report the first synthesis of the (3′R)-10 diastereomer and a set of related epimers, with the goal of defining the Stereochemical role of the 3′-sugar hydroxyl g
