16748-05-3Relevant academic research and scientific papers
Oxytocin and Lysine-vasopressin with N5,N5-Dialkylglutamine in the 4 Position: Effect of Introducing Sterically Hindered Groups into the Hydrophilic Cluster of Neurohypophyseal Hormones
Stahl, Glenn L.,Smith, Clark W.,Walter, Roderich,Tsegenidis, theodor,Stavropoulos, George,et al.
, p. 213 - 217 (2007/10/02)
The synthesis and pharmacological potencies of oxytocin and lysine-vasopressin analogues are reported in which the N5-amide of their glutaminyl residues are dialkylated.These analogues have been studied as an ongoing exploration of the biologic
Catalytic hydrogenolysis of protected sulfur containing peptides
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, (2008/06/13)
The use of catalytic hydrogenolysis to selectively deblock protected moieties in sulfur containing compounds has not been a practical process due to poisoning of the catalyst by the sulfur compound. It has now been found that catalytic hydrogenolysis of sulfur compounds can be successfully carried out by conducting the reaction in liquid ammonia as solvent.
