167484-48-2

Basic information

• Product Name: 1'-(3-(S)-(4-fluorophenyl)-4-(N-(3,5-bistrifluoromethylbenzoyl)(methylamino))butyl)-1-acetyl-spiro(indoline-3,4'-piperidine)
• Synonyms: 1'-(3-(S)-(4-fluorophenyl)-4-(N-(3,5-bistrifluoromethylbenzoyl)(methylamino))butyl)-1-acetyl-spiro(indoline-3,4'-piperidine)
• CAS NO: 167484-48-2
• Molecular Weight: 649.652
• Mol File: 167484-48-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1'-(3-(S)-(4-fluorophenyl)-4-(N-(3,5-bistrifluoromethylbenzoyl)(methylamino))butyl)-1-acetyl-spiro(indoline-3,4'-piperidine)(CAS DataBase Reference)
• NIST Chemistry Reference: 1'-(3-(S)-(4-fluorophenyl)-4-(N-(3,5-bistrifluoromethylbenzoyl)(methylamino))butyl)-1-acetyl-spiro(indoline-3,4'-piperidine)(167484-48-2)
• EPA Substance Registry System: 1'-(3-(S)-(4-fluorophenyl)-4-(N-(3,5-bistrifluoromethylbenzoyl)(methylamino))butyl)-1-acetyl-spiro(indoline-3,4'-piperidine)(167484-48-2)

Safety Data

• Hazardous Substances Data: 167484-48-2(Hazardous Substances Data)

Upstream product

• 167484-19-7 1-acetyl-spiro[2,3-dihydro-1H-indol-3,4'-piperidine] 
• 167484-47-1 4-Bromo-2-(S)-(4-fluorophenyl)-1-(N-(3,5-bistrifluoromethylbenzoyl)-methylamino)butane 
• 167484-18-6 benzyl spiro[indoline-3,4’-piperidine]-1‘-carboxylate 
• 167484-46-0 3-(S)-(4-Fluorophenyl)-4-(N-(3,5-bistrifluoromethylbenzoyl)methylamino)butanol 

Relevant articles and documents

Spiro-substituted azacycles as neurokinin antagonists

Disclosed are spiro-substituted azacycles of formula I are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of formula I are shown to be neurokinin antagonists.