167683-63-8 Usage
Uses
Used in Pharmaceutical Industry:
3-(2,6-Difluorophenyl)propionic Acid is used as an analgesic and anti-inflammatory agent for managing pain and inflammation associated with various conditions, including arthritis. Its mechanism of action involves the inhibition of prostaglandin production, thereby reducing the sensations of pain and the inflammatory response.
Used in Healthcare:
3-(2,6-Difluorophenyl)propionic Acid is utilized in the form of oral formulations such as tablets and capsules. It is commonly prescribed by healthcare professionals for the treatment of different types of pain and inflammation, offering relief to patients through its targeted action on prostaglandins.
However, it is important to note that 3-(2,6-Difluorophenyl)propionic Acid may have potential side effects, which necessitates its cautious use. Individuals with a history of stomach ulcers, kidney problems, or heart disease should exercise particular caution when considering this medication for pain and inflammation management.
Check Digit Verification of cas no
The CAS Registry Mumber 167683-63-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,6,8 and 3 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 167683-63:
(8*1)+(7*6)+(6*7)+(5*6)+(4*8)+(3*3)+(2*6)+(1*3)=178
178 % 10 = 8
So 167683-63-8 is a valid CAS Registry Number.
167683-63-8Relevant academic research and scientific papers
Direct synthesis of 3-arylpropionic acids by tetraphosphine/palladium catalysed Heck reactions of aryl halides with acrolein ethylene acetal
Lemhadri, Mhamed,Doucet, Henri,Santelli, Maurice
, p. 11533 - 11540 (2007/10/03)
Through the use of [PdCl(C3H5)]2/Cis,cis, cis-1,2,3,4-tetrakis(diphenylphosphinomethyl)cyclopentane as a catalyst, a range of aryl bromides undergoes Heck reaction with acrolein ethylene acetal. With this acetal, the selective formation of 3-arylpropionic acids/esters was observed. The functional group tolerance on the aryl halide is remarkable; substituents such as fluoro, methyl, methoxy, acetyl, formyl, benzoyl, nitro or nitrile are tolerated. Furthermore, this catalyst can be used at low loading, even for reactions of sterically hindered aryl bromides. Graphical Abstract.
