167702-25-2

Upstream product

• 33170-68-2 1,3-bis-(4-bromo-phenyl)-propane-1,3-dione 
• 586-76-5 4-Bromobenzoic acid 
• 586-75-4 4-chlorobenzoyl chloride 
• 619-42-1 4-methoxycarbonylphenyl bromide 

Downstream Products

• 183614-49-5 Bis-(4-bromobenzoyl)-chloromethanesulfenyl chloride 

Relevant academic research and scientific papers

New Dithio-bis-(diaroylmethanes) and Acetyl Diaroylchloromethyl Bisulfides: Attractive Synthons and Precursors for the Liberation of Highly Reactive Dithiiranes or Thiosulfines

In a new, feasible procedure five symmetrical para-substituted diaroylmethanes ((4-X-C6H4-CO)2-CH2; X = F, Cl, Br, CH3, and CH3O) are prepared, in most cases in very good yields. For purification and activation, they are converted into the copper(II) complexes of their enolates. Subsequently, three reaction steps with disulfur dichloride (S2Cl2), chlorine, and ethanethioic acid yield new CH-acidic dithio-bis-(diaroylmethanes), α-chlorosulfenic acid chlorides, and acetyl diaroylchloromethyl disulfides. The latter compounds are of interest for the liberation of highly reactive dithiirane/thiosulfine species. With thiomorpholine, α-chlorosulfenic acid chlorides give α-chlorosulfenic acid amides.

APPROACHES TO THE LIBERATION OF THIOSULFINES

In 1979 A.Senning found a series of reactions that involve probably thiosulfines of thiocarbonyl S-sulfides.Now, disulfide 5a was chosen for a re-examination, as no rearrangements seem to be involved.F, Cl, Br, CH3, and CH3O are used to change the electro