167708-86-3

Upstream product

• 40400-13-3 2-Iodobenzyl bromide 
• 873-55-2 sodium benzenesulfonate 
• 615-37-2 ortho-methylphenyl iodide 

Downstream Products

• 226089-83-4 2-(2-benzenesulfonylmethyl-phenylethynyl)-naphthalene 
• 869472-15-1 ethyl 2-(2-iodophenyl)-2-phenylsulfonylacetate 
• 226089-81-2 1-phenylethynyl-2-(phenylsulfonylmethyl)benzene 
• 1178576-97-0 4-benzenesulfonyl-1-phenyl-2,3-dihydro-1H-pyrazolo[1,5-b]isoquinolin-9-one 
• 1178576-98-1 4-benzenesulfonyl-3-methyl-1-phenyl-2,3-dihydro-1H-pyrazolo[1,5-b]isoquinolin-9-one 
• 1178576-99-2 4-benzenesulfonyl-1-methyl-2,3-dihydro-1H-pyrazolo[1,5-b]isoquinolin-9-one 
• 35324-46-0 o,o’-diiodo-diphenylacetylene 

Relevant academic research and scientific papers

An Efficient Straightforward Synthesis of Benzazulene

Benzazulene (1) is synthesized in five steps (cf.Scheme 2) starting from commercially available 2-iodobenzyl alcohol (4) and tropylium tetrafluoroborate in an overall yield of 44percent.The key step (cf. also Scheme 1) is the intramolecular Heck reacti

Palladium-catalyzed carboxamidation reaction and aldol condensation reaction cascade: A facile approach to ring-fused isoquinolinones

(Chemical Equation Presented) Palladium-catalyzed carboxamidation reaction and aldol condensation reaction cascade are very useful for the synthesis of various ABC ring substituted fused isoquinolinones.

Synthesis of indenes by the palladium-catalyzed carboannulation of internal alkynes

(Chemical Equation Presented) A number of highly substituted indenes have been prepared in good yields by treating functionally substituted aryl halides with various internal alkynes in the presence of a palladium catalyst. The reaction is believed to proceed by regioselective arylpalladation of the alkyne and subsequent nucleophilic displacement of the palladium in the resulting vinylpalladium intermediate.

Double elimination protocol for convenient synthesis of dihalodiphenylacetylenes: Versatile building blocks for tailor-made phenylene-ethynylenes

Dihalodiphenylacetylenes are conveniently synthesized by a double elimination reaction of β-substituted sulfones which are readily obtained from halogen-substituted benzyl sulfone and benzaldehyde derivatives. Halogens can be incorporated at any desired positions in the diphenylacetylene skeleton simply by choosing the substitution position of the halogen on the aromatic rings of the starting compounds. The diphenylacetylenes with different halogen substituents thus obtained undergo sequential carbon-carbon bond formations due to the different reactivities of the halogens. Thus, various moieties can be incorporated on the diphenylacetylene skeleton at whichever positions so that a variety of tailor-made phenylene-ethynylenes with regulated structure and composition could be designed.

Efficient new protocol to synthesize aromatic and heteroaromatic dithioesters

A very efficient, high yielding procedure to synthesize substituted aromatic and heteroaromatic dithioesters is described. It involves the reaction between (phenylsulfonyl)methyl (hetero)aromatic derivatives and elemental sulfur in basic medium, followed by alkylation.